What is Acquired Hemophilia 13 (Hemorrhagic Acquired Factor 13 Deficiency)?.
نویسندگان
چکیده
منابع مشابه
Factor 13 deficiency with severe hemorrhagic diathesis.
A HEMORRHAGIC DIATHESIS due to a congenital deficiency of fibrin stabilizing factor (f.s.f.) was first described in 1960 by Duckert et al.1 Five other cases were discovered since, in different cOuntries.2'6 The fibrin stabilizing factor (Lorand-Laki factor, fibrinase of Loewy), known and investigated in vitro for almost 20 years,7-11 was accepted in 1963 as one of the clotting factors-i.e. Fact...
متن کاملAcquired Hemophilia
To the Editor, I would like to highlight 3 of our patients, a 14-year-old boy and females of 4 and 41 years old [1,2] with acquired hemophilia B seen at İhsan Doğramacı Children’s Hospital (previously Hacettepe) between 1963 and 1973 among 343 patients with hemophilia [3] on account of the case of acquired hemophilia A in a 78-year-old man who was successfully treated with a combined immunosupp...
متن کاملAcquired hemophilia.
Acquired hemophilia is a very rare disease characterized by the presence of an autoantibody (mainly IgG) to factor VIII, with a clinical presentation resembling hemophilia A. It is associated with various autoimmune or dermatologic diseases, pregnancy, cancer, or drug ingestion, but in almost 50% of patients no underlying disorder is found. The treatment of acquired hemophilia is particularly c...
متن کاملAcquired Hemophilia A: A Frequently Overlooked Autoimmune Hemorrhagic Disorder
Acquired hemophilia A (AHA) is a rare hemorrhagic disease in which autoantibodies against coagulation factor VIII- (FVIII-) neutralizing antibodies (inhibitors) impair the intrinsic coagulation system. As the inhibitors developed in AHA are autoantibodies, the disease may have an autoimmune cause and is often associated with autoimmune disease. Although acute hemorrhage associated with AHA may ...
متن کاملAcquired Hemophilia A
Acquired hemophilia A is a rare but often life-threatening hemorrhagic disorder characterized by an auto antibody directed against coagulation factor VIII. Fifty per cent of cases are idiopathic whereas the remaining 50% are associated with pregnancy, autoimmune conditions, malignancies and drugs [1]. Acquired hemophilia is significantly rarer than the inherited form, affecting around 2 per mil...
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ژورنال
عنوان ژورنال: Nihon Naika Gakkai Zasshi
سال: 2010
ISSN: 0021-5384,1883-2083
DOI: 10.2169/naika.99.1934